Dexamethasone Jekiseni
Composition
Imwe neimwe ml ine:
Dexamethasone sodium phosphate 2 mg.
Excipients kusvika 1 ml.
Tsanangudzo
Mvura isina ruvara yakajeka.
Pharmacological chiito
Mushonga unoshandisa hunyanzvi hwekuita nekupinda uye kusunga kune cytoplasmic receptor protein uye unokonzera shanduko yemaitiro musteroid receptor complex.Shanduko yechimiro iyi inobvumira kutama kwayo mukati memukati uye yobva yasunga kune dzakati nzvimbo paDNA izvo zvinotungamira mukunyorwa kweiyo chaiyo m-RNA uye inozopedzisira yagadzirisa mapuroteni synthesis.Inoshandisa yakanyanya kusarudza glucocorticoid chiito.Inosimudzira ma enzymes anodiwa kuderedza mhinduro yekuzvimba.
Zviratidzo
Metabolic kusagadzikana, kusingatapukirwe kuzvimba maitiro, kunyanya acute musculoskeletal kuzvimba, allergic mamiriro, kushushikana uye kuvhunduka mamiriro.Serubatsiro muzvirwere zvinotapukira.Induction of parturition in ruminants panguva yekupedzisira yekuzvitakura.
Dosage uye kutonga
Yejekiseni remutsinga kana kuti intramuscular.
Mombe : 5-20mg (2.5-10ml) panguva.
Mabhiza: 2.5-5mg (1.25-2.5ml) panguva.
Katsi : 0.125-0.5mg (0.0625-0.25ml) panguva.
Imbwa: 0.25-1mg (0.125-0.5ml) panguva.
Side effect uye contraindication
Kunze kwekurapwa kwekukurumidzira, usashandise mumhuka dzine chisingaperi nephritis uye hyper-corticalism (Cushing's Syndrome).Kuvapo kwe congestive heart failure, chirwere cheshuga, uye osteoporosis zvipingamupinyi zvishoma.Usashandise muhutachiona hwehutachiona panguva yeviremic stage.
Kuchenjerera
Kungwarira kunofanira kutorwa kudzivirira netsaona kuzvibaya jekiseni.
Kana vial yave yakabikwa, zvirimo zvinofanirwa kushandiswa mukati memazuva makumi maviri nemasere.
Rasa chero chigadzirwa chisina kushandiswa uye midziyo isina chinhu.
Geza maoko mushure mekushandisa.
Withdrawal Period
Nyama: 21 mazuva.
Mukaka: 72 maawa.
Storage
Chengetedza munzvimbo inotonhorera uye yakaoma iri pasi pe30 ℃.
